Sarcopenia and Risk of Cognitive Impairment: Cohort Study and Mendelian Randomization Analysis
Our study suggests that sarcopenia is a potential causal risk factor for cognitive impairment, with physical activity acting as a modifiable mediator in this relationship.
Authors
- Tingting Sha (ORCID: https://orcid.org/0000-0002-8559-2150)
- Yuqing Zhang (ORCID: https://orcid.org/0000-0001-7638-0888)
- Chao Zeng (ORCID: https://orcid.org/0000-0003-4889-5731)
- Guanghua Lei (ORCID: https://orcid.org/0000-0003-2987-138X)
- Jie Wei (ORCID: https://orcid.org/0000-0003-3510-8241)
- Yilun Wang (ORCID: https://orcid.org/0000-0002-9468-4110)
- Changjun Li (ORCID: https://orcid.org/0000-0003-2718-0921)
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Harvard University (US)
- Central South University (CN)
- Hunan University (CN)
- Massachusetts General Hospital (US)
- Xiangya Hospital Central South University (CN)
Publication Details
- Journal
- JMIR Aging
- Published
- 2025-06-11
- DOI
- https://doi.org/10.2196/66031
- Citations
- 5
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 5.82