Association of Leucocyte Telomere Length With Stroke, Dementia, and Late-Life Depression
Individuals with shorter LTL are at increased risk of stroke, dementia, and LLD. Improved modifiable risk factor profiles seem to mitigate the impact of LTL on these diseases. Future research should explore the effectiveness of lifestyle interventions in mitigating adverse biological aging effects on brain health.
Authors
- Christopher D. Anderson (ORCID: https://orcid.org/0000-0002-0053-2002)
- Jonathan Rosand (ORCID: https://orcid.org/0000-0002-1014-9138)
- Sanjula Singh (ORCID: https://orcid.org/0000-0001-9304-8107)
- Savvina Prapiadou (ORCID: https://orcid.org/0000-0001-7415-2566)
- Jasper R. Senff (ORCID: https://orcid.org/0009-0002-6540-480X)
- Benjamin Yong‐Qiang Tan (ORCID: https://orcid.org/0000-0003-1824-9077)
- Christina Kourkoulis (ORCID: https://orcid.org/0000-0001-6330-9169)
- Tamara N. Kimball (ORCID: https://orcid.org/0000-0002-1107-0771)
- Reinier W. P. Tack (ORCID: https://orcid.org/0000-0003-3204-0309)
Institutions
- Broad Institute (US)
- Agency for Science, Technology and Research (SG)
- National University of Singapore (SG)
- University Medical Center Utrecht (NL)
- Massachusetts General Hospital (US)
- Mass General Brigham (US)
- Institute of Molecular and Cell Biology (SG)
Publication Details
- Journal
- Neurology
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1212/wnl.0000000000213794
- Citations
- 2
- Primary Topic
- Telomeres, Telomerase, and Senescence
- Type
- article
- Field-Weighted Citation Impact
- 2.33