Ferritin promotes monocyte osteoclastogenic differentiation to aggravate alveolar bone resorption in periodontitis
Ferritin and RANKL synergistically promote monocyte osteoclastogenesis, driving alveolar bone resorption in periodontitis. Targeting ferritin signaling may offer therapeutic potential to mitigate bone loss.
Authors
- Zhaoguo Yue (ORCID: https://orcid.org/0000-0002-9348-8599)
- Jianxia Hou (ORCID: https://orcid.org/0000-0003-2414-0895)
- Xiaochi Chang
- Wenxue Huang
- Mingming Hu (ORCID: https://orcid.org/0000-0002-6626-9657)
- Jie Zhang (ORCID: https://orcid.org/0009-0001-3657-4984)
- Ye Han (ORCID: https://orcid.org/0000-0003-2644-9431)
Institutions
- Capital Medical University (CN)
- Peking University (CN)
- Stomatology Hospital (CN)
- Beijing Shijitan Hospital (CN)
Publication Details
- Journal
- Journal of Dental Sciences
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1016/j.jds.2025.05.034
- Primary Topic
- Oral and gingival health research
- Type
- article
- Field-Weighted Citation Impact
- 0.00