Successful Transcatheter Pulmonary Valve Implantation in a Patient with Mechanical Valve in Aortic Position

The Harmony™ transcatheter pulmonary valve (TPV) is specifically designed to treat severe pulmonary regurgitation in a native or surgically repaired right ventricular outflow tract. To date, no reports have described TPV implantation (TPVI) in patients with prior aortic valve replacement (AVR) using a mechanical valve. Therefore, the risks of technical challenges or complications, particularly coronary compression or device fracture associated with prior AVR, remain unknown. This is the first report of successful TPVI using a Harmony™ TPV in a 52-year-old Asian man diagnosed with tetralogy of Fallot (TOF) who had previously undergone AVR following TOF repair with no associated technical difficulties or complications.

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Publication Details

Journal
Internal Medicine
Published
2025-06-11
DOI
https://doi.org/10.2169/internalmedicine.5381-25
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
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article

Successful Transcatheter Pulmonary Valve Implantation in a Patient with Mechanical Valve in Aortic Position

Mike Saji, Kanako Kishiki, Mamoru Nanasato, Naoki Wada et al.
Internal Medicine
Cardiac Valve Diseases and Treatments
article

Successful Transcatheter Pulmonary Valve Implantation in a Patient with Mechanical Valve in Aortic Position

Mike Saji, Kanako Kishiki, Mamoru Nanasato, Naoki Wada, Tadahiro Yoshikawa, Satoshi Yazaki, Yuriko Shima
article en

Abstract

The Harmony™ transcatheter pulmonary valve (TPV) is specifically designed to treat severe pulmonary regurgitation in a native or surgically repaired right ventricular outflow tract. To date, no reports have described TPV implantation (TPVI) in patients with prior aortic valve replacement (AVR) using a mechanical valve. Therefore, the risks of technical challenges or complications, particularly coronary compression or device fracture associated with prior AVR, remain unknown. This is the first report of successful TPVI using a Harmony™ TPV in a 52-year-old Asian man diagnosed with tetralogy of Fallot (TOF) who had previously undergone AVR following TOF repair with no associated technical difficulties or complications.

Internal MedicineVol. 65(1)
Toho University (JP), Sakakibara Hospital (JP)
Openalex Percentile: Top 77%
Cardiac Valve Diseases and Treatments
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