Kinetic resolution of trifluoromethylated heterobenzhydrols <i>via</i> hydrogen-acceptor-free Ir-catalyzed heteroaryl-selective C–H silylation

We experimentally and computationally investigated the kinetic resolution of trifluoromethylated heterobenzhydrols, bearing both phenyl and thiophene rings, via heteroaryl-selective C–H silylation.

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Publication Details

Journal
Organic Chemistry Frontiers
Published
2025-01-01
DOI
https://doi.org/10.1039/d5qo00725a
Primary Topic
Fluorine in Organic Chemistry
Type
article
Field-Weighted Citation Impact
0.00

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article

Kinetic resolution of trifluoromethylated heterobenzhydrols via hydrogen-acceptor-free Ir-catalyzed heteroaryl-selective C–H silylation

Yoshihiko Yamamoto, Ryu Tadano, Takeshi Yasui
Organic Chemistry Frontiers
Fluorine in Organic Chemistry
article

Kinetic resolution of trifluoromethylated heterobenzhydrols via hydrogen-acceptor-free Ir-catalyzed heteroaryl-selective C–H silylation

Yoshihiko Yamamoto, Ryu Tadano, Takeshi Yasui
article en

Abstract

We experimentally and computationally investigated the kinetic resolution of trifluoromethylated heterobenzhydrols, bearing both phenyl and thiophene rings, via heteroaryl-selective C–H silylation.

Organic Chemistry FrontiersVol. 12(20)
Nagoya University (JP)
Japan Agency for Medical Research and Development, Japan Society for the Promotion of Science
Openalex Percentile: Top 90%
Fluorine in Organic Chemistry
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