An Unusual Cause of Abdominal Pain: Mesenteric Lymphadenopathy Secondary to Sarcoidosis Without Pulmonary Involvement

Sarcoidosis is a systemic disease that affects multiple organs in the body but rarely affects the gastrointestinal (GI) tract. The symptoms of GI sarcoidosis may be nonspecific or silent. Often, it is discovered on computed tomography (CT) or esophagogastroduodenoscopy (EGD), and a biopsy is needed for diagnosis. Initial management is typically with prednisone; however, here, we present a rare case of GI sarcoidosis with mesenteric lymphadenopathy in the absence of pulmonary involvement, diagnosed via biopsy and treated successfully with methotrexate.

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Publication Details

Journal
Cureus
Published
2025-06-11
DOI
https://doi.org/10.7759/cureus.85797
Primary Topic
Sarcoidosis and Beryllium Toxicity Research
Type
article
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article

An Unusual Cause of Abdominal Pain: Mesenteric Lymphadenopathy Secondary to Sarcoidosis Without Pulmonary Involvement

Fady Banno, Brandon Wiggins, John M. Sullivan, Nathan Landesman et al.
Cureus
Sarcoidosis and Beryllium Toxicity Research
article

An Unusual Cause of Abdominal Pain: Mesenteric Lymphadenopathy Secondary to Sarcoidosis Without Pulmonary Involvement

Fady Banno, Brandon Wiggins, John M. Sullivan, Nathan Landesman, Kyle Knight, Chris Cenzer
article en

Abstract

Sarcoidosis is a systemic disease that affects multiple organs in the body but rarely affects the gastrointestinal (GI) tract. The symptoms of GI sarcoidosis may be nonspecific or silent. Often, it is discovered on computed tomography (CT) or esophagogastroduodenoscopy (EGD), and a biopsy is needed for diagnosis. Initial management is typically with prednisone; however, here, we present a rare case of GI sarcoidosis with mesenteric lymphadenopathy in the absence of pulmonary involvement, diagnosed via biopsy and treated successfully with methotrexate.

CureusVol. 17(6)
Henry Ford Health System (US), Beaumont Hospital, Royal Oak (US)
Good health and well-being
Openalex Percentile: Top 83%
Sarcoidosis and Beryllium Toxicity Research
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