Effect of fluoride toothpaste and mouthwash on the cytotoxicity of buccal mucosa cells in the presence of nickel-titanium archwires during comprehensive orthodontic treatment: A randomized clinical trial

The use of fluoride mouthwash and toothpaste in the presence of stainless-steel attachments and nickel-titanium archwire decreased the buccal cell viability by 8.51 % and increased the micronucleus score by 3.03 %. The use of fluoride toothpaste and mouthwash had a significant cytotoxicity effect on buccal mucosa cells in the presence of nickel-titanium archwire during comprehensive orthodontic treatment.

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Publication Details

Journal
Journal of Oral Biology and Craniofacial Research
Published
2025-06-11
DOI
https://doi.org/10.1016/j.jobcr.2025.06.007
Primary Topic
Anesthesia and Neurotoxicity Research
Type
article
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article

Effect of fluoride toothpaste and mouthwash on the cytotoxicity of buccal mucosa cells in the presence of nickel-titanium archwires during comprehensive orthodontic treatment: A randomized clinical trial

Jitendra Sharan, Ashok Kumar Jena, Mayur Bhola, Madhusmita Sethy
Journal of Oral Biology and Craniofacial Research
Anesthesia and Neurotoxicity Research
article

Effect of fluoride toothpaste and mouthwash on the cytotoxicity of buccal mucosa cells in the presence of nickel-titanium archwires during comprehensive orthodontic treatment: A randomized clinical trial

Jitendra Sharan, Ashok Kumar Jena, Mayur Bhola, Madhusmita Sethy
article en

Abstract

The use of fluoride mouthwash and toothpaste in the presence of stainless-steel attachments and nickel-titanium archwire decreased the buccal cell viability by 8.51 % and increased the micronucleus score by 3.03 %. The use of fluoride toothpaste and mouthwash had a significant cytotoxicity effect on buccal mucosa cells in the presence of nickel-titanium archwire during comprehensive orthodontic treatment.

Journal of Oral Biology and Craniofacial ResearchVol. 15(4)
All India Institute of Medical Sciences Bhubaneswar (IN)
Openalex Percentile: Top 85%
Anesthesia and Neurotoxicity Research
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