Genomic dissection of nosocomial multiclonal-outbreak by carbapenem-resistant Pseudomonas aeruginosa strains in a tertiary children’s hospital in Japan
Molecular epidemiological data have revealed a multilineage outbreak of P. aeruginosa strains that independently developed carbapenem resistance. This emphasises the rapid evolution of antimicrobial resistance in P. aeruginosa in response to the antimicrobial doses administered to patients who are hospitalised.
Authors
- Hidetada Hirakawa
- Akihiko Shimizu (ORCID: https://orcid.org/0000-0003-3261-4616)
- Haruyoshi Tomita (ORCID: https://orcid.org/0000-0001-9969-2235)
- Takahiro Nomura (ORCID: https://orcid.org/0000-0002-5733-332X)
- Jun Kurushima (ORCID: https://orcid.org/0000-0002-8573-6169)
- Yusuke Hashimoto (ORCID: https://orcid.org/0000-0002-1086-9995)
- Natsuko Ota
- Koichi Tanimoto
- Naoko Tomie
Institutions
- Gunma University (JP)
- Gunma Children's Medical Center (JP)
- Gunma University of Health and Welfare (JP)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1016/j.jgar.2025.05.026
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.00