Transcriptomic analysis reveals shared deregulated neutrophil responses in COVID-19 and idiopathic pulmonary fibrosis

By delineating both shared and disease-specific molecular pathways, our findings validate the critical role of neutrophils in COVID-19 and IPF pathophysiology, highlighting their involvement in balancing the inflammatory response across diverse lung diseases.

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Publication Details

Journal
Respiratory Research
Published
2025-06-11
DOI
https://doi.org/10.1186/s12931-025-03180-2
Citations
1
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
Field-Weighted Citation Impact
1.52

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article

Transcriptomic analysis reveals shared deregulated neutrophil responses in COVID-19 and idiopathic pulmonary fibrosis

Evgenia Synolaki, Argyrios Tzouvelekis, Dimitrios T. Boumpas, Georgios Divolis et al.
1 citations
Respiratory Research
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
1.52
article

Transcriptomic analysis reveals shared deregulated neutrophil responses in COVID-19 and idiopathic pulmonary fibrosis

Evgenia Synolaki, Argyrios Tzouvelekis, Dimitrios T. Boumpas, Georgios Divolis, Panagiotis Skendros, Ioanna E. Galani, Rodoula Tringidou
article en
1 citations

Abstract

By delineating both shared and disease-specific molecular pathways, our findings validate the critical role of neutrophils in COVID-19 and IPF pathophysiology, highlighting their involvement in balancing the inflammatory response across diverse lung diseases.

Respiratory ResearchVol. 26(1)
Democritus University of Thrace (GR), University of Patras (GR), Academy of Athens (GR), Biomedical Research Foundation of the Academy of Athens (GR), University Hospital of Alexandroupolis (GR)
European Commission, State Scholarships Foundation
Openalex Percentile: Top 17%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
1.52
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