Engineered pH-buffering nanocomposite for robust one-pot multi-enzyme cascade synthesis of γ-aminobutyric acid
This work develops a PMAA@ZIF-8 nanocomposite that creates localized acidic microenvironments to overcome pH incompatibility in multi-enzyme cascades, enabling 93.6% GABA yield, efficient NADH regeneration and enhanced enzyme stability.
Authors
- Yanxin Gao (ORCID: https://orcid.org/0000-0001-9269-5273)
- Fan Yang (ORCID: https://orcid.org/0000-0003-3106-7593)
- Liyun Zhang (ORCID: https://orcid.org/0000-0001-5882-2179)
- Wenjin Li (ORCID: https://orcid.org/0000-0002-7103-8781)
- Hang Luo (ORCID: https://orcid.org/0000-0003-3942-2844)
- Tin Pou Lai
Institutions
- Nankai University (CN)
Publication Details
- Journal
- Green Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5gc02022k
- Citations
- 2
- Primary Topic
- Electrochemical sensors and biosensors
- Type
- article
- Field-Weighted Citation Impact
- 1.46