The necessity of adjuvant surgery for patients with high-risk chemorefractory or relapsed gestational choriocarcinoma with complete remission after anti-PD-1 therapy

These results suggest that surgical resection of drug-resistant lesions may not be necessary in patients with high-risk chemorefractory or relapsed choriocarcinoma who achieve CR after anti-PD-1 therapy.

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Publication Details

Journal
Journal of Gynecologic Oncology
Published
2025-01-01
DOI
https://doi.org/10.3802/jgo.2025.36.e130
Primary Topic
Gestational Trophoblastic Disease Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

The necessity of adjuvant surgery for patients with high-risk chemorefractory or relapsed gestational choriocarcinoma with complete remission after anti-PD-1 therapy

Yonglan He, Xirun Wan, Jiayuan Zhao, Dan Wang et al.
Journal of Gynecologic Oncology
Gestational Trophoblastic Disease Studies
article

The necessity of adjuvant surgery for patients with high-risk chemorefractory or relapsed gestational choriocarcinoma with complete remission after anti-PD-1 therapy

Yonglan He, Xirun Wan, Jiayuan Zhao, Dan Wang, Yang Xiang, Jun Zhao, Junjun Yang
article en

Abstract

These results suggest that surgical resection of drug-resistant lesions may not be necessary in patients with high-risk chemorefractory or relapsed choriocarcinoma who achieve CR after anti-PD-1 therapy.

Journal of Gynecologic OncologyVol. 36(6)
Chinese Academy of Medical Sciences & Peking Union Medical College (CN), Peking Union Medical College Hospital (CN)
National Natural Science Foundation of China, Peking Union Medical College Hospital, National Key Research and Development Program of China
Openalex Percentile: Top 81%
Gestational Trophoblastic Disease Studies
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The necessity of adjuvant surgery for patients with high-risk chemorefractory or relapsed gestational choriocarcinoma with complete remission after anti-PD-1 therapy — Yonglan He, Xirun Wan, et al. · Journal of Gynecologic Oncology (2025) | TGRS Research Map | TGRS