Exploring the Neuroprotective Potential of Polyphenolic Compounds in Mitigating Quinolinic Acid-Induced Neurotoxicity in Alzheimer's Disease
Lycopene and Cur-Zn are promising candidates for AD therapy, demonstrating not only anti-oxidant activity but also a capacity to minimise the neurotoxic effects of QA, offering a dual mechanism of action. Further, <i>in-vivo</i> studies are needed to validate their therapeutic potential in neurodegenerative diseases.
Authors
- Pallav Gandhi
- Shital S. Panchal (ORCID: https://orcid.org/0000-0003-4211-8202)
Institutions
- Nirma University (IN)
Publication Details
- Journal
- Current Alzheimer Research
- Published
- 2025-05-01
- DOI
- https://doi.org/10.2174/0115672050383383250529100802
- Primary Topic
- Cholinesterase and Neurodegenerative Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00