Complete remission of nonmetastatic persistent gestational trophoblastic tumour by Methotrexate and Actinomycin D:A case report

Locally invasive non-metastatic persistent gestational trophoblastic tumours (PGTT) usually falls in low risk group in WHO scoring system based on prognostic factors. We report a case of non-metastatic PGTT which followed a molar pregnancy.Complete remission of the tumour was achieved by 3 cycles of single agent chemotherapy (Methotrexate with leukovorin rescue) and 5 cycles of single agent ( Actinomycin D).

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Publication Details

Journal
Journal of Karnali Academy of Health Sciences
Published
2025-06-07
DOI
https://doi.org/10.61814/jkahs.v8i1.969
Primary Topic
Gestational Trophoblastic Disease Studies
Type
article
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article

Complete remission of nonmetastatic persistent gestational trophoblastic tumour by Methotrexate and Actinomycin D:A case report

Bijal Shah, Ganesh Dangal, Aruna Karki, Ranjana Shrestha et al.
Journal of Karnali Academy of Health Sciences
Gestational Trophoblastic Disease Studies
article

Complete remission of nonmetastatic persistent gestational trophoblastic tumour by Methotrexate and Actinomycin D:A case report

Bijal Shah, Ganesh Dangal, Aruna Karki, Ranjana Shrestha, Kabin Bhattachan
article en

Abstract

Locally invasive non-metastatic persistent gestational trophoblastic tumours (PGTT) usually falls in low risk group in WHO scoring system based on prognostic factors. We report a case of non-metastatic PGTT which followed a molar pregnancy.Complete remission of the tumour was achieved by 3 cycles of single agent chemotherapy (Methotrexate with leukovorin rescue) and 5 cycles of single agent ( Actinomycin D).

Journal of Karnali Academy of Health SciencesVol. 8(1)
Women's Hospital (US), Maternity and Children's Hospital (SA), National Academy of Medical Sciences (NP), Sobhraj Maternity Hospital (PK), Kathmandu Medical College Teaching Hospital (NP)
Openalex Percentile: Top 81%
Gestational Trophoblastic Disease Studies
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