Percutaneous valve intervention for severe mitral regurgitation complicated by lung sepsis

Evidence review: Clinical and Costeffectiveness and Adverse Events associated with percutaneous mitral valve leaflet repair for severe degenerative mitral regurgitation (MitraClip)* All interventions used in single armed studies were percutaneous edge to edge repair of mitral valve using MitraClip.** Results in italics exactly match those requested in scope.*** Included studies were generally well reported (hence highly scored), but this scoring system does not take into account biases and sources of confounding inherent to registry and observational studies. Applicability score of most relevant subgroup analysed.