Answering real-world clinical questions using large language model, retrieval-augmented generation, and agentic systems
Synergistic systems combining RAG-based evidence summarization and agentic generation of novel evidence could improve the availability of pertinent evidence for patient care.
Authors
- Adam P. Yan (ORCID: https://orcid.org/0000-0001-8300-3095)
- Rahul V. Nene (ORCID: https://orcid.org/0000-0002-0093-4714)
- Gavin Hui (ORCID: https://orcid.org/0000-0002-4818-4254)
- Amy R. Zipursky (ORCID: https://orcid.org/0000-0002-3003-2818)
- Nigam H. Shah (ORCID: https://orcid.org/0000-0001-9385-7158)
- Saurabh Gombar (ORCID: https://orcid.org/0000-0002-5581-8569)
- Vladimir Polony
- Robert Brown (ORCID: https://orcid.org/0000-0001-7960-5755)
- Hadeel Hassan (ORCID: https://orcid.org/0000-0002-8266-1659)
- Dong-han Yao (ORCID: https://orcid.org/0000-0002-5468-807X)
- C. William Pike (ORCID: https://orcid.org/0000-0002-2166-1559)
- Yen Low
- Michael L. Jackson (ORCID: https://orcid.org/0000-0002-2340-0256)
- Jananee Muralidharan (ORCID: https://orcid.org/0000-0003-1437-7717)
- Dan C. Derieg
- Courtney J. Pokrzywa
- Shivam Vedak
- Christina Dinh
- Philip Ballentine (ORCID: https://orcid.org/0009-0007-3596-6453)
- Rehan N. Chawdry
- Rebecca J. Hyde
- Neil Sanghavi
- Morgan Pike
- Jordan Davies
- Natasha Alexander
- Brigham B. Hyde
- Julian D Baldwin (ORCID: https://orcid.org/0009-0008-0446-4271)
Institutions
- University of California, Los Angeles (US)
- University of Michigan (US)
- Hospital for Sick Children (CA)
- University of California San Diego (US)
- SickKids Foundation (CA)
- Institute for Clinical Evaluative Sciences (CA)
- Columbia University (US)
- Stanford University (US)
Publication Details
- Journal
- Digital Health
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1177/20552076251348850
- Citations
- 22
- Primary Topic
- Artificial Intelligence in Healthcare and Education
- Type
- article
- Field-Weighted Citation Impact
- 14.40