Outcomes of Emergent Stenting with Antiplatelet Therapy in Patients with Large Vessel Occlusion Stroke with or without Intravenous Tissue Plasminogen Activator

Among patients who received emergent stenting with antiplatelet therapy, successful reperfusion was achieved more frequently in the IV tPA group than in the no-IV tPA group, although the former exhibited a higher SICH rate and worse functional outcomes. These findings suggest that prior IV tPA administration may increase the risk of hemorrhagic complications in cases requiring emergent stenting with antiplatelet therapy.

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Publication Details

Journal
Journal of Neuroendovascular Therapy
Published
2025-01-01
DOI
https://doi.org/10.5797/jnet.oa.2024-0039
Primary Topic
Acute Ischemic Stroke Management
Type
article
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article

Outcomes of Emergent Stenting with Antiplatelet Therapy in Patients with Large Vessel Occlusion Stroke with or without Intravenous Tissue Plasminogen Activator

Masaomi Koyanagi, Yuki Takano, Masanori Goto, T. Takamatsu et al.
Journal of Neuroendovascular Therapy
Acute Ischemic Stroke Management
article

Outcomes of Emergent Stenting with Antiplatelet Therapy in Patients with Large Vessel Occlusion Stroke with or without Intravenous Tissue Plasminogen Activator

Masaomi Koyanagi, Yuki Takano, Masanori Goto, T. Takamatsu, Nobuyuki Fukui, Satoru Fujiwara, Kunimasa Teranishi, Satohiro Kawade, Nobuyuki Sakai, Tadashi Sunohara, Mai Yoshimoto, Jun‐ichi Takeda, Ryu Fukumitsu, Rikuo Nishii, Yasuhiro Yamamoto, Nobuyuki Ohara, Tsuyoshi Ohta, Yuji Naramoto, Kota Nakajima, H. Tomita, Masanori Tokuda
article en

Abstract

Among patients who received emergent stenting with antiplatelet therapy, successful reperfusion was achieved more frequently in the IV tPA group than in the no-IV tPA group, although the former exhibited a higher SICH rate and worse functional outcomes. These findings suggest that prior IV tPA administration may increase the risk of hemorrhagic complications in cases requiring emergent stenting with antiplatelet therapy.

Journal of Neuroendovascular TherapyVol. 19(1)
Kobe City Medical Center General Hospital (JP)
Good health and well-being
Openalex Percentile: Top 81%
Acute Ischemic Stroke Management
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Outcomes of Emergent Stenting with Antiplatelet Therapy in Patients with Large Vessel Occlusion Stroke with or without Intravenous Tissue Plasminogen Activator — Masaomi Koyanagi, Yuki Takano, et al. · Journal of Neuroendovascular Therapy (2025) | TGRS Research Map | TGRS