Estimating the optimal cutoff for the IGT‐AD Distress subscale adapted for amyloid PET results disclosure
The Impact of Genetic Testing for Alzheimer's Disease (IGT-AD) instrument is widely used to assess the psychological impact of Alzheimer's disease biomarker disclosure.Establishing a cutoff score is essential for identifying individuals needing psychological support.Receiver operating characteristic analysis determined the optimal IGT-AD distress cutoff, using Impact of Event Scale (cutoff = 26) as the gold standard.The optimal cutoff for moderate to severe distress on the adapted IGT-AD is 15.Larger studies are needed to validate this cutoff.
Authors
- Kim Jeong Eun
- Jennifer H. Lingler
- Dianxu Ren (ORCID: https://orcid.org/0000-0002-1160-8922)
- Joshua D. Grill (ORCID: https://orcid.org/0000-0002-4215-7589)
Institutions
- University of Pittsburgh (US)
- University of California, Irvine (US)
Publication Details
- Journal
- Alzheimer s & Dementia Translational Research & Clinical Interventions
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/trc2.70116
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute on Aging