Strong gradients, cool performance: A 64‐channel array coil with concurrent field monitoring and thermal control for ex vivo diffusion‐weighted brain imaging using the 3T connectome 2.0 MRI scanner
We describe an integrated hardware approach for addressing higher order field perturbations, thermal instability, and SNR challenges in human ex vivo whole brain dMRI under high-diffusion sensitizing gradient conditions. This approach combines an anatomically optimized multichannel receive array, concurrent field monitoring, and active temperature stabilization. Enhanced image quality and improved reliability of quantitative MR imaging were demonstrated with this comprehensive hardware solution.
Authors
- Chaimaa Chemlali (ORCID: https://orcid.org/0000-0002-2896-7155)
- Lawrence L. Wald (ORCID: https://orcid.org/0000-0001-8278-6307)
- Mirsad Mahmutović (ORCID: https://orcid.org/0000-0001-9178-4194)
- Sam-Luca Hansen (ORCID: https://orcid.org/0000-0002-5353-5573)
- Choukri Mekkaoui (ORCID: https://orcid.org/0000-0001-8597-9219)
- Jason Stockmann (ORCID: https://orcid.org/0000-0001-8454-5347)
- Dongsuk Sung (ORCID: https://orcid.org/0000-0001-6287-2144)
- Boris Keil (ORCID: https://orcid.org/0000-0003-0805-8330)
- Gabriel Ramos‐Llordén (ORCID: https://orcid.org/0000-0003-4020-705X)
- Alina Scholz (ORCID: https://orcid.org/0000-0002-3324-6889)
- Anastasia Yendiki (ORCID: https://orcid.org/0000-0003-1386-3828)
- Susie Y. Huang (ORCID: https://orcid.org/0000-0003-2950-7254)
- Anpreet Ghotra (ORCID: https://orcid.org/0000-0001-6445-9062)
- M Shrestha
- Mona Alem
Institutions
- Harvard University (US)
- Philipps University of Marburg (DE)
- Massachusetts General Hospital (US)
- Harvard–MIT Division of Health Sciences and Technology (US)
- Athinoula A. Martinos Center for Biomedical Imaging (US)
- Technische Hochschule Mittelhessen (DE)
- Massachusetts Institute of Technology (US)
Publication Details
- Journal
- Magnetic Resonance in Medicine
- Published
- 2025-06-08
- DOI
- https://doi.org/10.1002/mrm.30599
- Citations
- 3
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 4.08
Funders
- Deutsche Forschungsgemeinschaft
- Hessisches Ministerium für Wissenschaft und Kunst
- National Institute of Biomedical Imaging and Bioengineering