Invasive Rhinocerebral Mucormycosis in Carcinoma Base of Tongue Patient: A Rare Case Report

Introduction A 24-year-old male undergoing treatment for carcinoma at the base of the tongue developed invasive mucormycosis (IM), a rare and severe fungal infection. While common in haematological malignancies, this condition is rarely reported in solid cancers. Primary Diagnoses, Interventions and Outcomes Diagnosis was established through radiological investigations, potassium hydroxide staining and histopathological examination of the infected tissue. He was treated with liposomal amphotericin B, surgical debridement and supportive care measures. Conclusion This case highlights the critical need for early recognition and prompt management of IM in patients with solid malignancies undergoing intensive cancer therapy, where the index of suspicion is low. Enhanced clinical vigilance and a multidisciplinary approach are essential for improving outcomes.

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Journal
Journal of Current Oncology
Published
2024-12-01
DOI
https://doi.org/10.1177/25898892251340211
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

Invasive Rhinocerebral Mucormycosis in Carcinoma Base of Tongue Patient: A Rare Case Report

Parveen Ahlawat, Shaifali Mahajan, Shamima Akhter, Munish Gairola et al.
Journal of Current Oncology
Antifungal resistance and susceptibility
article

Invasive Rhinocerebral Mucormycosis in Carcinoma Base of Tongue Patient: A Rare Case Report

Parveen Ahlawat, Shaifali Mahajan, Shamima Akhter, Munish Gairola, Sarthak Tandon, Neelam Sachdeva, Shreya Rai, Mudit Agarwal, Meenakshi Kamboj
article en

Abstract

Introduction A 24-year-old male undergoing treatment for carcinoma at the base of the tongue developed invasive mucormycosis (IM), a rare and severe fungal infection. While common in haematological malignancies, this condition is rarely reported in solid cancers. Primary Diagnoses, Interventions and Outcomes Diagnosis was established through radiological investigations, potassium hydroxide staining and histopathological examination of the infected tissue. He was treated with liposomal amphotericin B, surgical debridement and supportive care measures. Conclusion This case highlights the critical need for early recognition and prompt management of IM in patients with solid malignancies undergoing intensive cancer therapy, where the index of suspicion is low. Enhanced clinical vigilance and a multidisciplinary approach are essential for improving outcomes.

Journal of Current OncologyVol. 7(2)
Rajiv Gandhi Cancer Institute and Research Centre (IN)
Good health and well-being
Openalex Percentile: Top 67%
Antifungal resistance and susceptibility
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