Influence of Macrotroponin on the 99th Percentile Threshold in 2 High-Sensitivity Cardiac Troponin Assays

Macrotroponin significantly influenced the Siemens Atellica hs-cTnI 99th percentiles, suggesting important clinical implications that warrant further prospective studies. The 99th/50th percentile ratio may help evaluate macrotroponin interference in troponin assays.

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Publication Details

Journal
Clinical Chemistry
Published
2025-05-21
DOI
https://doi.org/10.1093/clinchem/hvaf068
Citations
3
Primary Topic
Acute Myocardial Infarction Research
Type
article
Field-Weighted Citation Impact
4.16

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article

Influence of Macrotroponin on the 99th Percentile Threshold in 2 High-Sensitivity Cardiac Troponin Assays

Linda Hilsted, Shoaib Afzal, Ola Hammarsten, Jonas Henrik Kristensen et al.
3 citations
Clinical Chemistry
Acute Myocardial Infarction Research
4.16
article

Influence of Macrotroponin on the 99th Percentile Threshold in 2 High-Sensitivity Cardiac Troponin Assays

Linda Hilsted, Shoaib Afzal, Ola Hammarsten, Jonas Henrik Kristensen, Aditi Banerjee, Rasmus Bo Hasselbalch, Martin Overgaard, Henning Bundgaard, Nina Strandkjær, Pia R. Kamstrup, Camilla Jannie Kobylecki, Morten Dahl, Allan S. Jaffe, Kasper Karmark Iversen, Søren Ladefoged, Morten Bagge Hansen, Sophie Sander Knudsen, Alexander Holst Kronborg
article en
3 citations

Abstract

Macrotroponin significantly influenced the Siemens Atellica hs-cTnI 99th percentiles, suggesting important clinical implications that warrant further prospective studies. The 99th/50th percentile ratio may help evaluate macrotroponin interference in troponin assays.

Clinical ChemistryVol. 71(8)
University of Copenhagen (DK), Odense University Hospital (DK), Herlev Hospital (DK), Aarhus University Hospital (DK), Rigshospitalet (DK), Zealand University Hospital (DK), Mayo Clinic in Arizona (US), University of Gothenburg (SE)
Hjerteforeningen, Danmarks Frie Forskningsfond, Sahlgrenska Universitetssjukhuset, Helsefonden
Good health and well-being
Openalex Percentile: Top 6%
Acute Myocardial Infarction Research
4.16
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