Advancing Aneurysm Neck Healing: Evidence from Drug-Eluting Stent Technologies

Subarachnoid haemorrhage resulting from intracranial aneurysms (IAs) represents the third most prevalent acute cerebrovascular disease with high mortality and disability rates, following ischaemic stroke and hypertensive intracerebral haemorrhage.Cerebral aneurysms pose a significant threat to public health in China, imposing substantial economic burdens on families and society.Current treatment modalities predominantly include surgical clipping and endovascular intervention, with the latter emerging as the primary therapeutic approach.Studies indicate that standalone coil embolisation is associated with a slightly higher postoperative recurrence rate compared to stent-assisted coiling, largely due to incomplete endothelial coverage at the aneurysm neck.To enhance endothelialisation at the aneurysm neck and mitigate risks of rupture and recanalisation, recent research has focused on applying advanced coating materials to bare metal stents, aiming to promote neointimal formation at the diseased arterial segment.This article provides a retrospective analysis of the efficacy of various stent coating materials in facilitating postoperative endothelialisation at the aneurysm neck.