Improved Sampling Method to Enhance the Positive Rate of HER2 Detection in Gastric Cancer
The improved sampling method significantly improves the positive HER2 expression rate (1+) in gastric cancer specimens, thereby reducing false-negative HER2 detection rates by immunohistochemistry. This method warrants further clinical implementation, particularly in resource-limited settings.
Authors
- Xiaowen Wen (ORCID: https://orcid.org/0000-0001-9099-2987)
- Yuehong Qin
- Jie Chai
- Bai-Lin Liu (ORCID: https://orcid.org/0000-0003-1240-8516)
- Shijiang Wang (ORCID: https://orcid.org/0000-0002-1020-1178)
- Huan Shi (ORCID: https://orcid.org/0000-0002-7520-8776)
- Xu Sun (ORCID: https://orcid.org/0000-0002-2832-642X)
- Liqing Liu (ORCID: https://orcid.org/0000-0001-6140-738X)
- Xilin Song
- Longgang Wang
- Kai Liu (ORCID: https://orcid.org/0000-0003-2933-0356)
Institutions
- Shandong Tumor Hospital (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Discovery Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.24976/discov.med.202537197.95
- Primary Topic
- Gene expression and cancer classification
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Beijing Xisike Clinical Oncology Research Foundation
- Shandong Academy of Medical Sciences