S100A8 Mediates Autophagy and Apoptosis in Ovarian Cancer Cells via the PI3K/Akt Pathway

With its ability to inhibit proliferation, migration, and autophagy, and promote apoptosis in OC cells by inhibiting the PI3K/Akt pathway, S100A8 holds promise as a potential target for the prevention and treatment of OC, providing an effective therapeutic strategy for the clinic.

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Publication Details

Journal
Discovery Medicine
Published
2025-01-01
DOI
https://doi.org/10.24976/discov.med.202537197.99
Citations
2
Primary Topic
S100 Proteins and Annexins
Type
article
Field-Weighted Citation Impact
1.61
Controls
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article

S100A8 Mediates Autophagy and Apoptosis in Ovarian Cancer Cells via the PI3K/Akt Pathway

Guangwen Cao, Xiaojie Ma, Yu Wu
2 citations
Discovery Medicine
S100 Proteins and Annexins
1.61
article

S100A8 Mediates Autophagy and Apoptosis in Ovarian Cancer Cells via the PI3K/Akt Pathway

Guangwen Cao, Xiaojie Ma, Yu Wu
article en
2 citations

Abstract

With its ability to inhibit proliferation, migration, and autophagy, and promote apoptosis in OC cells by inhibiting the PI3K/Akt pathway, S100A8 holds promise as a potential target for the prevention and treatment of OC, providing an effective therapeutic strategy for the clinic.

Discovery MedicineVol. 37(197)
Shaoxing City Women and Children Hospital (CN), Jiangxi Pingxiang People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 17%
S100 Proteins and Annexins
1.61
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