Combined Oral Contraceptives Modulate Apoptosis via IL-11/PI3K/AKT Pathway in Rat With Premature Ovarian Insufficiency
Our findings demonstrated that COCs protect ovarian granulosa cells from apoptosis in rats with POI, an effect mediated through the IL-11/PI3K/AKT signaling cascade.
Authors
- Meiling Chen
- Fang You (ORCID: https://orcid.org/0000-0001-5718-0952)
- Li Zhang (ORCID: https://orcid.org/0000-0002-9386-8938)
- Fan Zhang (ORCID: https://orcid.org/0000-0003-0120-4892)
- Li Zeng (ORCID: https://orcid.org/0000-0002-9039-6509)
Institutions
- Guiyang College of Traditional Chinese Medicine (CN)
- Guiyang Medical University (CN)
- Affiliated Hospital of Guizhou Medical University (CN)
Publication Details
- Journal
- Discovery Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.24976/discov.med.202537197.96
- Primary Topic
- Reproductive System and Pregnancy
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Guizhou University