MicroRNA-18b regulates cell cycle progression in papillary thyroid carcinoma by targeting <i>CDK2</i>: an <i>in vitro</i> experimental study
Our findings underscore miR-18b's potential as a biomarker for predicting the prognosis of PTC and suggest that it functions through direct regulation of <i>CDK2</i>, influencing cell cycle dynamics. This study not only enhances our understanding of miR-18b in thyroid cancer but also highlights its potential in refining prognostic evaluations and therapeutic strategies.
Authors
- Han-Gil Kim (ORCID: https://orcid.org/0000-0002-6394-942X)
- Ji‐Ho Park (ORCID: https://orcid.org/0000-0002-2751-7320)
- Jin-Kyu Cho (ORCID: https://orcid.org/0000-0002-6877-7620)
- Dong-Hwan Kim (ORCID: https://orcid.org/0000-0002-2151-0048)
- Chi‐Young Jeong (ORCID: https://orcid.org/0000-0003-4121-6695)
- Youngsim Son (ORCID: https://orcid.org/0009-0008-3063-7164)
- Seung-Jin Kwag (ORCID: https://orcid.org/0000-0002-9267-9158)
- Sang‐Ho Jeong (ORCID: https://orcid.org/0000-0001-9061-6236)
- Young‐Joon Lee (ORCID: https://orcid.org/0000-0002-1735-3385)
- Young‐Tae Ju (ORCID: https://orcid.org/0000-0002-1785-8500)
- Jae‐Myung Kim (ORCID: https://orcid.org/0000-0002-9012-8176)
- Ju-Yeon Kim (ORCID: https://orcid.org/0000-0002-5846-7522)
- Eun‐Jung Jung (ORCID: https://orcid.org/0000-0001-8413-613X)
Institutions
- Changwon National University (KR)
- Gyeongsang National University (KR)
- Gyeongsang National University Hospital (KR)
Publication Details
- Journal
- Annals of Surgical Treatment and Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.4174/astr.2025.108.6.374
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- Gyeongsang National University
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea