An optimizing lentiviral titer determination assay based on Raji cells

Raji cells offer a more reliable and efficient platform for lentiviral titration compared to the conventional HEK293T-based method. This suspension cell-based approach holds potential for enhancing the scalability and consistency of lentiviral vector production in gene therapy.

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Publication Details

Journal
American Journal of Translational Research
Published
2025-01-01
DOI
https://doi.org/10.62347/ztkm3637
Primary Topic
Virus-based gene therapy research
Type
article
Field-Weighted Citation Impact
0.00

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article

An optimizing lentiviral titer determination assay based on Raji cells

Quan Chen
American Journal of Translational Research
Virus-based gene therapy research
article

An optimizing lentiviral titer determination assay based on Raji cells

Quan Chen
article en

Abstract

Raji cells offer a more reliable and efficient platform for lentiviral titration compared to the conventional HEK293T-based method. This suspension cell-based approach holds potential for enhancing the scalability and consistency of lentiviral vector production in gene therapy.

American Journal of Translational ResearchVol. 17(5)
Army Medical University (CN), Kunming Medical University (CN), Daping Hospital (CN)
National Natural Science Foundation of China, Army Medical University
Zero hunger
Openalex Percentile: Top 85%
Virus-based gene therapy research
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