Sarcoma, ex pleomorphic adenoma of parotid gland: A rare entity

Sarcomas arising in a parotid gland is an uncommon occurrence and a sarcomatous transformation in a recurring pleomorphic adenoma is even rare. Diagnosis of salivary gland tumors has proven to be challenging. Pleomorphic adenomas (PA) are the most commonly diagnosed tumors of the salivary gland and a malignant transformation in preexisting or recurring ones is even thinner on the ground. Malignant transformations in a pleomorphic adenoma can occur in carcinomas, carcinosarcomas, or sarcomas. We are sharing an interesting case of a 68-year-old male with a parotid region swelling with a history of recurring pleomorphic adenomas. There was seen a sarcomatous transformation in pleomorphic adenoma which was proven on IHC. A correlation among cytopathology, histopathology, and previous clinical history is been tendered in our case report.

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Publication Details

Journal
Indian Journal of Pathology and Microbiology
Published
2025-06-07
DOI
https://doi.org/10.4103/ijpm.ijpm_1008_23
Primary Topic
Salivary Gland Tumors Diagnosis and Treatment
Type
article
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article

Sarcoma, ex pleomorphic adenoma of parotid gland: A rare entity

Vikram Narang, Aminder Singh, Harpreet Kaur, Mehar Ghuman
1 links
Indian Journal of Pathology and Microbiology
Salivary Gland Tumors Diagnosis and Treatment
article

Sarcoma, ex pleomorphic adenoma of parotid gland: A rare entity

Vikram Narang, Aminder Singh, Harpreet Kaur, Mehar Ghuman
article en

Abstract

Sarcomas arising in a parotid gland is an uncommon occurrence and a sarcomatous transformation in a recurring pleomorphic adenoma is even rare. Diagnosis of salivary gland tumors has proven to be challenging. Pleomorphic adenomas (PA) are the most commonly diagnosed tumors of the salivary gland and a malignant transformation in preexisting or recurring ones is even thinner on the ground. Malignant transformations in a pleomorphic adenoma can occur in carcinomas, carcinosarcomas, or sarcomas. We are sharing an interesting case of a 68-year-old male with a parotid region swelling with a history of recurring pleomorphic adenomas. There was seen a sarcomatous transformation in pleomorphic adenoma which was proven on IHC. A correlation among cytopathology, histopathology, and previous clinical history is been tendered in our case report.

Indian Journal of Pathology and MicrobiologyVol. 68(4)
Dayanand Medical College & Hospital (IN)
Good health and well-being
Openalex Percentile: Top 77%
Salivary Gland Tumors Diagnosis and Treatment
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