Syndemic Synergy of HPV, HIV, and HSV-2 for Oncogenic HPV Replication in Female Sex Workers
FSWs exhibit a high burden of HR-HPV, shaped by co-infections with HIV and HSV-2. HSV-2 independently drives HR-HPV replication, highlighting its role in HPV persistence and cervical cancer risk. Integrated HSV-2 detection and Gardasil-9<sup>®</sup> vaccination should be prioritized in cervical cancer elimination strategies targeting high-risk populations in sub-Saharan Africa.
Authors
- Hugues Loemba (ORCID: https://orcid.org/0000-0001-9251-2908)
- Serge Tonen‐Wolyec (ORCID: https://orcid.org/0000-0002-7734-7729)
- Ralph‐Sydney Mboumba Bouassa (ORCID: https://orcid.org/0000-0002-3956-6189)
- Jérémie Muwonga (ORCID: https://orcid.org/0000-0002-0800-6146)
- Laurent Bélec (ORCID: https://orcid.org/0000-0002-3950-2513)
- Jonathan Muwonga Tukisadila
Institutions
- Délégation Paris 5 (FR)
- University of Ottawa (CA)
- Université Paris Cité (FR)
- Montfort Hospital (CA)
- University of Kinshasa (CD)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hôpital Européen Georges-Pompidou (FR)
- Hôpital Européen (FR)
- Centre International de Recherches Médicales de Franceville (GA)
- Institut du Savoir Montfort (CA)
Publication Details
- Journal
- Tropical Medicine and Infectious Disease
- Published
- 2025-06-07
- DOI
- https://doi.org/10.3390/tropicalmed10060157
- Citations
- 2
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 2.71