Relationship between vitamin D and osteoarthritis
Our study demonstrated that low blood vitamin D levels (insufficiency/deficiency) were associated with a more severe knee OA. These patients had a large body weight, BMI, higher VAS pain values, WOMAC index (overall and its components), worse KOOS, PGHC, and smaller cartilage sizes in the medial parts of the knee joint (according to ultrasound); such patients were significantly more likely to have osteitis in the medial parts of the femur and tibia according to MRI. Also, stage II and III knee OA and OA of other localizations, clinically detected synovitis, quadriceps hypotrophy, and flat feet were more common.
Authors
- А. М. Лила (ORCID: https://orcid.org/0000-0002-6068-3080)
- Н. Г. Кашеварова (ORCID: https://orcid.org/0000-0001-8732-2720)
- E. Strebkova (ORCID: https://orcid.org/0000-0001-8130-5081)
- Н. В. Демин (ORCID: https://orcid.org/0000-0003-0961-9785)
- С. И. Глухова (ORCID: https://orcid.org/0000-0002-4285-0869)
- D. Kudinsky (ORCID: https://orcid.org/0000-0002-1084-3920)
- О. Г. Алексеева (ORCID: https://orcid.org/0000-0003-1852-1798)
- Л. И. Алексеева (ORCID: https://orcid.org/0000-0001-7017-0898)
- Kirill M. Mikhaylov (ORCID: https://orcid.org/0009-0000-1481-7749)
- Е. А. Таскина (ORCID: https://orcid.org/0000-0001-8218-3223)
- E. Yu. Samarkina (ORCID: https://orcid.org/0000-0001-7501-9185)
- Н. М. Савушкина (ORCID: https://orcid.org/0000-0001-8562-6077)
- E. P. Sharapova (ORCID: https://orcid.org/0000-0003-4242-8278)
Institutions
- Russian Medical Academy of Continuous Professional Education (RU)
- Association of Rheumatologists of Russia (RU)
Publication Details
- Journal
- Terapevticheskii arkhiv
- Published
- 2025-06-08
- DOI
- https://doi.org/10.26442/00403660.2025.05.203228
- Primary Topic
- Vitamin D Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00