Construction of mitochondrial-targeted ferritin carrier: subunit-terminal fused mitochondrial presequences facilitate efficient delivery
This vector inspired by natural mitochondrial protein sorting represents an optimal hierarchical delivery system for targeting both tumor and mitochondrial, offering a dependable alternative for precise treatment strategies in mitochondrial diseases.
Authors
- Mengyuan Xu (ORCID: https://orcid.org/0000-0002-1479-2243)
- Xiangyu Zhao (ORCID: https://orcid.org/0000-0002-2186-476X)
- Xinning Fang
- Xiaole Qi (ORCID: https://orcid.org/0000-0002-5799-8604)
- Zhenghong Wu (ORCID: https://orcid.org/0000-0002-0244-329X)
- Yitong Li (ORCID: https://orcid.org/0000-0003-3402-4484)
- Han Yu (ORCID: https://orcid.org/0000-0002-4229-0806)
- Jia Zeng (ORCID: https://orcid.org/0000-0002-9447-2791)
Institutions
- China Pharmaceutical University (CN)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1016/j.jare.2025.06.015
- Citations
- 1
- Primary Topic
- Trace Elements in Health
- Type
- article
- Field-Weighted Citation Impact
- 1.12
Funders
- National Natural Science Foundation of China