Nickel Promoted Green and One Pot Reaction Process: Construction of Pyrazoles Derivatives

Through a one-pot multi-component approach, we accomplished a nickel-promoted simple, new, and efficient protocol for constructing pyrano[2,3-c] pyrazoles. Various aldehydes are treated under optimized reaction conditions via condensation and addition reactions to provide final compounds 5a-j in good to high yield. Mechanistic studies have been discussed in this methodology.

Publication Details

Journal
Biointerface Research in Applied Chemistry
Published
2025-04-15
DOI
https://doi.org/10.33263/briac152.027
Primary Topic
Multicomponent Synthesis of Heterocycles
Type
article
Field-Weighted Citation Impact
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article

Nickel Promoted Green and One Pot Reaction Process: Construction of Pyrazoles Derivatives

Biointerface Research in Applied Chemistry
Multicomponent Synthesis of Heterocycles
article

Nickel Promoted Green and One Pot Reaction Process: Construction of Pyrazoles Derivatives

article en

Abstract

Through a one-pot multi-component approach, we accomplished a nickel-promoted simple, new, and efficient protocol for constructing pyrano[2,3-c] pyrazoles. Various aldehydes are treated under optimized reaction conditions via condensation and addition reactions to provide final compounds 5a-j in good to high yield. Mechanistic studies have been discussed in this methodology.

Biointerface Research in Applied ChemistryVol. 15(2)
Openalex Percentile: Top 90%
Multicomponent Synthesis of Heterocycles
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Nickel Promoted Green and One Pot Reaction Process: Construction of Pyrazoles Derivatives · Biointerface Research in Applied Chemistry (2025) | TGRS Research Map | TGRS