Immunomodulatory Effect of a Bifido- and Lactobacilli Complex on Nonspecific Humoral Immunity of Sturgeon Fish Hybrids

The effect of a bifido- and lactobacilli complex on some indices of nonspecific humoral immunity of the sturgeon hybrid Acipenser gueldaenstaedti Brandt × A. baeri Brandt has been studied. The level of antimicrobial properties, C-reactive protein, and lysozyme and the content of nonspecific immune complexes in serum were studied. This study showed a high level of bacteriostatic activity and lysozyme, a low content of nonspecific immune complexes in the experimental groups compared to the control, which indicates the immunostimulating effect of the bifidobacteria and lactobacilli complex on nonspecific mechanisms of the antibacterial defense of fish.

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Journal
Biology Bulletin
Published
2025-04-01
DOI
https://doi.org/10.1134/s1062359024612199
Primary Topic
Aquaculture disease management and microbiota
Type
article
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article

Immunomodulatory Effect of a Bifido- and Lactobacilli Complex on Nonspecific Humoral Immunity of Sturgeon Fish Hybrids

Anna Aleksandrovna Bakhareva, Yu. N. Grozesku, Т. А. Субботкина, S. V. Kuzmicheva et al.
Biology Bulletin
Aquaculture disease management and microbiota
article

Immunomodulatory Effect of a Bifido- and Lactobacilli Complex on Nonspecific Humoral Immunity of Sturgeon Fish Hybrids

Anna Aleksandrovna Bakhareva, Yu. N. Grozesku, Т. А. Субботкина, S. V. Kuzmicheva, Т. А. Суворова, Adelya Dzumaniyashevna Zhandalgarova, D. V. Mikryakov, М. Ф. Субботкин
article en

Abstract

The effect of a bifido- and lactobacilli complex on some indices of nonspecific humoral immunity of the sturgeon hybrid Acipenser gueldaenstaedti Brandt × A. baeri Brandt has been studied. The level of antimicrobial properties, C-reactive protein, and lysozyme and the content of nonspecific immune complexes in serum were studied. This study showed a high level of bacteriostatic activity and lysozyme, a low content of nonspecific immune complexes in the experimental groups compared to the control, which indicates the immunostimulating effect of the bifidobacteria and lactobacilli complex on nonspecific mechanisms of the antibacterial defense of fish.

Biology BulletinVol. 52(2)
Astrakhan State Technical University (RU), Institute of Biology of Inland Waters named Ivan Dmitrievich Papanin (RU), Moscow State University of Technologies and Management named after K.G. Razumovskiy (RU), K.G. Razumovsky Moscow State University of Technologies and Management (RU)
Openalex Percentile: Top 86%
Aquaculture disease management and microbiota
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