Mapping the impact: AI-driven quantification of geographic atrophy on OCT scans and its association with visual sensitivity loss
AI-driven, automated quantification of GA on OCT showed a strong correlation with the global extent of visual sensitivity loss, comparable with those based on manual annotations on FAF imaging. These findings affirm the expected functional relevance of OCT-derived GA measurements and their clinical utility for monitoring disease progression in those with GA.
Authors
- Pearse A. Keane (ORCID: https://orcid.org/0000-0002-9239-745X)
- Robbert Struyven (ORCID: https://orcid.org/0000-0002-2201-859X)
- Mark A. Chia (ORCID: https://orcid.org/0000-0003-0339-5186)
- Xavier Hadoux (ORCID: https://orcid.org/0000-0002-4524-3706)
- Dominic J. Williamson (ORCID: https://orcid.org/0000-0001-5219-9312)
- David A. Merle (ORCID: https://orcid.org/0000-0003-4485-5580)
- Robyn H. Guymer (ORCID: https://orcid.org/0000-0002-9441-4356)
- Peter van Wijngaarden (ORCID: https://orcid.org/0000-0002-8800-7834)
- Zhichao Wu (ORCID: https://orcid.org/0000-0002-8623-6684)
- Reena Chopra (ORCID: https://orcid.org/0000-0002-4264-8329)
- Maxime Jannaud
Institutions
- Moorfields Eye Hospital NHS Foundation Trust (GB)
- The University of Melbourne (AU)
- Medical University of Graz (AT)
- Centre for Eye Research Australia (AU)
- STZ eyetrial (DE)
- Moorfields Eye Hospital (GB)
- University College London (GB)
Publication Details
- Journal
- British Journal of Ophthalmology
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1136/bjo-2024-326603
- Citations
- 2
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.41
Funders
- BrightFocus Foundation
- Apellis Pharmaceuticals