TDSFE-Net: A Temporal Dual-Stream Feature Extraction Network for Depression Detection From EEG

Early detection and diagnosis are critical for effective depression management. Although electroence-phalography (EEG) can provide an objective basis for the auxiliary diagnosis of depression, decoding depression-related brain activity from EEG is a highly challenging task due to the inherent complexity, dynamism, and non-linearity. Therefore, this study introduces a novel temporal dual-stream feature extraction network (TDSFE-Net) that incorporates multiple attention mechanisms. Specially, we first develop a dynamic fusion weight based local-global attention mechanism into the hierarchiclal temporal-separable convolutional network (TSCN) to automatically capture the temporal dynamic characteristics of the EEG signal. Subsequently, a channel-wise module is designed to reveal the key temporal information in spatial dimensions. Finally, a softmax with full conected layer is used as classifier.The TDSFE-Net achieved impressive classification accuracies of 98.72%, 96.91%, and 99.53% on the MODMA, HUSM, and Hospital datasets, respectively. In addition, this study also reveals the pattern of correlation between the activity of specific brain regions and depression, providing a new perspective and scientific basis for discovering biomarkers and studying the neural mechanisms of depression.