Reverse T3 in patients with hypothyroidism on different thyroid hormone replacement

This study found elevated rT3 levels in patients with symptoms of fatigue on various thyroid hormone replacements with the highest levels of rT3 in those taking L-T4 replacement alone and the lowest levels of rT3 in those on preparations that contained L-T3 alone.

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Publication Details

Journal
PLoS ONE
Published
2025-06-09
DOI
https://doi.org/10.1371/journal.pone.0325046
Primary Topic
Thyroid Disorders and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Reverse T3 in patients with hypothyroidism on different thyroid hormone replacement

Theodore C. Friedman, Julian B. Wilson, Martin L. Lee, Thanh D. Hoang et al.
PLoS ONE
Thyroid Disorders and Treatments
article

Reverse T3 in patients with hypothyroidism on different thyroid hormone replacement

Theodore C. Friedman, Julian B. Wilson, Martin L. Lee, Thanh D. Hoang, Ma’ayan Epstein
article en

Abstract

This study found elevated rT3 levels in patients with symptoms of fatigue on various thyroid hormone replacements with the highest levels of rT3 in those taking L-T4 replacement alone and the lowest levels of rT3 in those on preparations that contained L-T3 alone.

PLoS ONEVol. 20(6)
University of California, Los Angeles (US), Walter Reed National Military Medical Center (US), University of California System (US), Charles R. Drew University of Medicine and Science (US), Fielding Graduate University (US)
National Institute on Drug Abuse, National Institute on Minority Health and Health Disparities
Good health and well-being
Openalex Percentile: Top 81%
Thyroid Disorders and Treatments
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Reverse T3 in patients with hypothyroidism on different thyroid hormone replacement — Theodore C. Friedman, Julian B. Wilson, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS