Nodal radioactivity after lymphoscintigraphy as a guide to sentinel node–positivity in melanoma patients
For accurate intraoperative identification of SNs containing metastatic melanoma, gamma counts may be unreliable. The key to accuracy is high-quality lymphoscintigraphy, ideally with SPECT-CT imaging, for precise preoperative identification and localization of SNs. Use of a gamma-detection probe intraoperatively will assist in the search for these pre-operatively identified SNs, but removal of only the "hottest" node will not reliably indicate whether regional node metastasis has occurred.
Authors
- Kerwin F. Shannon (ORCID: https://orcid.org/0000-0001-8538-3132)
- Gabrielle Williams (ORCID: https://orcid.org/0000-0001-9240-3648)
- Alison J. Potter (ORCID: https://orcid.org/0000-0001-5493-6021)
- John F. Thompson (ORCID: https://orcid.org/0000-0002-2816-2496)
- Sydney Ch’ng (ORCID: https://orcid.org/0000-0002-4011-1253)
- Julie R. Howle (ORCID: https://orcid.org/0000-0003-3634-246X)
- Thomas E. Pennington (ORCID: https://orcid.org/0000-0002-0210-057X)
- Omgo E. Nieweg
- David Chung (ORCID: https://orcid.org/0000-0002-7813-0986)
- Robyn P.M. Saw (ORCID: https://orcid.org/0000-0002-3354-806X)
- Richard A. Scolyer (ORCID: https://orcid.org/0000-0002-8991-0013)
- Andrew J. Spillane (ORCID: https://orcid.org/0000-0002-8354-434X)
- Kevin London (ORCID: https://orcid.org/0000-0003-4639-7966)
- Roger F. Uren
- Jonathan R. Stretch
Institutions
- New South Wales Department of Health (AU)
- Royal Prince Alfred Hospital (AU)
- Melanoma Institute Australia (AU)
Publication Details
- Journal
- European Journal of Surgical Oncology
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1016/j.ejso.2025.110225
- Citations
- 1
- Primary Topic
- Cutaneous Melanoma Detection and Management
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- Melanoma Institute Australia
- Medical Research Council
- National Health and Medical Research Council