An umbrella review of systematic reviews/meta-analyses evaluating the antimicrobial activity of various nanoparticles on orthodontic materials & components

The studies indicate that incorporating AgNP into orthodontic adhesives enhances antimicrobial activity but exhibits high heterogeneity, necessitating more in vivo studies. TiO<sub>2</sub>-coated brackets show antimicrobial properties against various pathogens. Nanoparticle-coated archwires with AgNP, N-doped TiO<sub>2</sub>, graphene oxide, and zinc oxide reduce demineralization, are biocompatible, and reduce surface roughness, showing good to fair antimicrobial activity. Results should be interpreted cautiously, and further clinical and long-term studies are required to confirm the effectiveness of these nanoparticles in preventing white spot lesions.

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Publication Details

Journal
Journal of Oral Biology and Craniofacial Research
Published
2025-06-09
DOI
https://doi.org/10.1016/j.jobcr.2025.06.002
Citations
3
Primary Topic
Dental materials and restorations
Type
article
Field-Weighted Citation Impact
5.03
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article

An umbrella review of systematic reviews/meta-analyses evaluating the antimicrobial activity of various nanoparticles on orthodontic materials & components

Ruchira Shreevats, Syed Azeemuddin, Vaibhav Kumar, Mohit Jaiswal et al.
3 citations
Journal of Oral Biology and Craniofacial Research
Dental materials and restorations
5.03
article

An umbrella review of systematic reviews/meta-analyses evaluating the antimicrobial activity of various nanoparticles on orthodontic materials & components

Ruchira Shreevats, Syed Azeemuddin, Vaibhav Kumar, Mohit Jaiswal, Meghna Vandekar
article en
3 citations

Abstract

The studies indicate that incorporating AgNP into orthodontic adhesives enhances antimicrobial activity but exhibits high heterogeneity, necessitating more in vivo studies. TiO<sub>2</sub>-coated brackets show antimicrobial properties against various pathogens. Nanoparticle-coated archwires with AgNP, N-doped TiO<sub>2</sub>, graphene oxide, and zinc oxide reduce demineralization, are biocompatible, and reduce surface roughness, showing good to fair antimicrobial activity. Results should be interpreted cautiously, and further clinical and long-term studies are required to confirm the effectiveness of these nanoparticles in preventing white spot lesions.

Journal of Oral Biology and Craniofacial ResearchVol. 15(4)
Navodaya Dental College and Hospital (IN), Health Strat (Kenya) (KE), Public Health Foundation of India (IN)
Openalex Percentile: Top 5%
Dental materials and restorations
5.03
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