Deciphering alternative splicing patterns during cell fate transition of fast chemical reprogramming
This research provided a comprehensive characterization of AS during FCR, highlighting the pivotal roles of AS in regulating cell fate transitions. Our findings advanced the understanding of the molecular mechanisms governing cell fate decisions and offered new insights into the potential of FCR for regenerative medicine and therapeutic applications.
Authors
- Yunkun Lu (ORCID: https://orcid.org/0000-0001-7605-1259)
- Junjie Li (ORCID: https://orcid.org/0000-0002-4862-2517)
- Tianyuan Pan
- Yeling Ruan
- Qianqian Wang (ORCID: https://orcid.org/0009-0005-8148-7176)
- Huizhen Zhang (ORCID: https://orcid.org/0000-0002-0255-1856)
- Sijie Feng (ORCID: https://orcid.org/0009-0001-0777-0687)
- Lianyu Lin (ORCID: https://orcid.org/0009-0004-5061-9298)
- Kainan Lin (ORCID: https://orcid.org/0009-0009-0124-1379)
Institutions
- Sir Run Run Shaw Hospital (CN)
- Henan Polytechnic University (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1186/s12915-025-02264-1
- Citations
- 2
- Primary Topic
- RNA Research and Splicing
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- Henan Polytechnic University
- Medical and Health Research Project of Zhejiang Province
- Natural Science Foundation of Zhejiang Province