Single-cell chromatin accessibility profiling reveals regulatory mechanisms and evolution in pig brains
Our research offers preliminary insights into the heterogeneity of pig brains and suggests the potential underlying regulatory mechanisms. Additionally, we explore the possible impact of nervous system differences on phenotypic changes, which could lay the groundwork for further biomedical studies.
Authors
- Fusheng Xiong (ORCID: https://orcid.org/0000-0001-7159-9522)
- Peng Zhou
- Yue Xiang (ORCID: https://orcid.org/0000-0001-6580-9378)
- Jiahui Sun
- Xinyun Li (ORCID: https://orcid.org/0000-0002-7943-1713)
- Saixian Zhang
- Liangliang Fu (ORCID: https://orcid.org/0000-0002-9878-1516)
- Jing Xu (ORCID: https://orcid.org/0000-0001-9845-3304)
- Shengquan Wang (ORCID: https://orcid.org/0000-0002-3841-7552)
- Xiaolong Qi (ORCID: https://orcid.org/0000-0003-1579-2939)
- Jingjin Li (ORCID: https://orcid.org/0009-0001-4118-1333)
- Yi‐Wen Huang (ORCID: https://orcid.org/0000-0002-5196-7030)
- Zhuqing Zheng (ORCID: https://orcid.org/0000-0002-4570-7646)
- Qiulin Zhao
Institutions
- Huazhong Agricultural University (CN)
- Agricultural Genomics Institute at Shenzhen (CN)
- Jingchu University of Technology (CN)
- Ministry of Agriculture (CA)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1186/s12915-025-02263-2
- Citations
- 2
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China