Therapeutic Choices in Systemic Sclerosis–Associated Interstitial Lung Disease, a Survey of 2 International Research Groups

First-line treatment preferences are in line with current treatment guidelines. CI therapy is not typically used, although the EVER-ILD trial might have influenced prescribing patterns with RTX/MMF CI therapy more typical. Prednisone use was more common than expected. Further studies evaluating combination MMF/TCZ versus MMF/RTX and whether TCZ is effective for SSc-ILD in patients without an inflammatory laboratory profile are necessary to help guide clinical practice. Further adoption of current guidelines may also change prednisone use patterns.

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Publication Details

Journal
JCR Journal of Clinical Rheumatology
Published
2025-06-09
DOI
https://doi.org/10.1097/rhu.0000000000002249
Primary Topic
Systemic Sclerosis and Related Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Therapeutic Choices in Systemic Sclerosis–Associated Interstitial Lung Disease, a Survey of 2 International Research Groups

Iazsmin Bauer Ventura, Michael Macklin, Dinesh Khanna
JCR Journal of Clinical Rheumatology
Systemic Sclerosis and Related Diseases
article

Therapeutic Choices in Systemic Sclerosis–Associated Interstitial Lung Disease, a Survey of 2 International Research Groups

Iazsmin Bauer Ventura, Michael Macklin, Dinesh Khanna
article en

Abstract

First-line treatment preferences are in line with current treatment guidelines. CI therapy is not typically used, although the EVER-ILD trial might have influenced prescribing patterns with RTX/MMF CI therapy more typical. Prednisone use was more common than expected. Further studies evaluating combination MMF/TCZ versus MMF/RTX and whether TCZ is effective for SSc-ILD in patients without an inflammatory laboratory profile are necessary to help guide clinical practice. Further adoption of current guidelines may also change prednisone use patterns.

JCR Journal of Clinical RheumatologyVol. 31(7)
University of Michigan (US), University of Chicago (US), Scleroderma Foundation (US), ORCID (US)
Openalex Percentile: Top 81%
Systemic Sclerosis and Related Diseases
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