Causality of genetically predicted solid cancers on risk of sepsis: insights from Mendelian randomization
Our findings suggest renal cancer is correlated with the occurrence of sepsis. This association is partially influenced by BMI and smoking. Unexpectedly, sepsis may act as a protective effect against renal cancer.
Authors
- Linjie Qiu (ORCID: https://orcid.org/0009-0008-9204-5690)
- Jia Zhong (ORCID: https://orcid.org/0000-0002-0464-3754)
- Shiyu Chen (ORCID: https://orcid.org/0000-0002-5394-6946)
- Yan Zhang (ORCID: https://orcid.org/0000-0003-2326-2225)
- Kai Zhang (ORCID: https://orcid.org/0000-0001-6818-377X)
Institutions
- Children's Hospital of Zhejiang University (CN)
- First Affiliated Hospital Zhejiang University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1007/s12672-025-02848-x
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province