Unveiling the immunopharmacological mechanisms of Danggui Yinzi (DGYZ) in treating chronic urticaria: insights from network pharmacology and experimental validation
This study, employing UPLC-Q-TOF-MS and both in vivo and in vitro experiments, provides a comprehensive analysis of the mechanism of DGYZ in CU. The findings indicate that DGYZ exerts therapeutic effects in CU by modulating immune responses. This research lays the foundation for a deeper understanding of its immunopharmacological mechanisms, potentially aiding the development of novel drugs and therapeutic strategies for CU management.
Authors
- Xurui Wang
- Anjing Chen (ORCID: https://orcid.org/0000-0001-8992-3220)
- Changchun Hou (ORCID: https://orcid.org/0000-0001-6234-3701)
- Yueyue Wang (ORCID: https://orcid.org/0000-0002-2178-3927)
- Ming Yue Li
Institutions
- University of Electronic Science and Technology of China (CN)
- Jiangsu Province Hospital (CN)
- Chengdu University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Chinese Medicine
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1186/s13020-025-01137-7
- Citations
- 2
- Primary Topic
- Urticaria and Related Conditions
- Type
- article
- Field-Weighted Citation Impact
- 3.34