Shared hub genes in membranous nephropathy and kidney renal clear cell carcinoma: investigating molecular overlap and tumor progression
Our findings identify FYN, LGALS8, MAGI2, and WT1 as hub genes in KIRC, with potential diagnostic and prognostic value. These genes play significant roles in methylation, mutation, and immune regulation in KIRC. However, the results from the limited MN samples suggest possible roles of these genes in MN pathology, but further studies are required to fully assess the relevance of these findings to MN.
Authors
- Hui Peng (ORCID: https://orcid.org/0000-0002-2000-1647)
- Shuwen Zhang (ORCID: https://orcid.org/0000-0002-5969-1737)
Institutions
- Zhejiang International Studies University (CN)
- Zhejiang Hospital (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1007/s12672-025-02701-1
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.00