HIV-1 drug resistance among people living with HIV receiving dolutegravir-based anti-retroviral regimens in Uganda: a national laboratory-based survey using remnant viral load samples, 2022
HIVDR to dolutegravir was uncommon but present among both children and adults with VNS after 9 months or more of exposure to dolutegravir. Additional longitudinal outcomes data are needed to determine if adherence counselling for patients with VNS on dolutegravir regimens might improve outcomes.
Authors
- Grace Namayanja (ORCID: https://orcid.org/0000-0003-0154-6788)
- Pontiano Kaleebu (ORCID: https://orcid.org/0000-0001-9706-2977)
- Hudson Balidawa
- Edward Mbidde
- Grace Sanyu
- Mina Ssali
- Christine Watera (ORCID: https://orcid.org/0000-0001-7791-8694)
- Alisen Ayitewala (ORCID: https://orcid.org/0000-0001-6173-4006)
- Elliot Raizes (ORCID: https://orcid.org/0000-0001-5121-877X)
- Du-Ping Zheng (ORCID: https://orcid.org/0009-0009-2233-8348)
- Christina Mwangi (ORCID: https://orcid.org/0000-0003-4733-318X)
- Mary Naluguza
- Cordelia Katureebe (ORCID: https://orcid.org/0000-0003-0184-5753)
- Jonathan Ntale (ORCID: https://orcid.org/0000-0003-0587-7373)
- Miriam Nabukenya
- Esther Nazziwa
- Deogratius Ssemwanga (ORCID: https://orcid.org/0000-0001-9675-4234)
- Juliet Asio (ORCID: https://orcid.org/0000-0001-6593-4937)
- Bill Elur (ORCID: https://orcid.org/0009-0006-2387-559X)
- Clement Zeh
- Maria Nanyonjo
- Stephanie Hackett (ORCID: https://orcid.org/0000-0002-8049-9416)
- Sherri Pals (ORCID: https://orcid.org/0000-0002-0003-6236)
- Juliana de Fatima Da Silva
Institutions
- Ministry of Health (UG)
- Centers for Disease Control and Prevention (UG)
- Uganda Virus Research Institute (UG)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1093/jac/dkaf180
- Citations
- 4
- Primary Topic
- HIV/AIDS drug development and treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.58
Funders
- Centers for Disease Control and Prevention