A novel strategy to combat insecticide resistance in insect pest with a nanoparticle‐based fusion <scp>dsRNA</scp> delivery system
This study introduces a gene-targeted insecticide resistance management strategy utilizing fusion dsRNA to disrupt metabolic resistance pathways. Its field efficacy underscores the potential of RNAi to restore insecticide effectiveness and represents a paradigm shift toward mechanism-driven pest control. © 2025 Society of Chemical Industry.
Authors
- Shun He (ORCID: https://orcid.org/0000-0003-4551-0744)
- Yuanli Xie
- M. M. Zhang
- Dan Sun (ORCID: https://orcid.org/0000-0002-5100-2749)
- Huazhong Zhou (ORCID: https://orcid.org/0000-0002-7713-503X)
- Chang Yu
- Hu Wan (ORCID: https://orcid.org/0000-0002-8123-3759)
- Guo‐Hua Hu (ORCID: https://orcid.org/0000-0002-1001-6386)
- Jianhong Li (ORCID: https://orcid.org/0000-0003-4354-9231)
- Qinghong Zeng (ORCID: https://orcid.org/0000-0001-5018-0079)
- Daqian He
Institutions
- Huazhong Agricultural University (CN)
- Institute of Plant Protection (CN)
- Wuhan Research Institute of Materials Protection (CN)
- Shanghai Zhangjiang Laboratory (CN)
Publication Details
- Journal
- Pest Management Science
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1002/ps.8966
- Citations
- 8
- Primary Topic
- Insect Resistance and Genetics
- Type
- article
- Field-Weighted Citation Impact
- 6.45
Funders
- National Natural Science Foundation of China