Construction of cartilaginous organoids based on cartilage extracellular matrix microcarriers to promote articular cartilage regeneration through immune regulation
This research involved the creation of CORGs utilizing natural biomaterials (ECM) and MSCs, demonstrating significant promise for treating cartilage injuries, thereby paving the way for innovative strategies in cartilage tissue regeneration engineering.
Authors
- Yue Tian (ORCID: https://orcid.org/0000-0001-6291-1676)
- L Chen
- Zhibo Jia
- Yingjie Xiong (ORCID: https://orcid.org/0009-0006-9089-028X)
- Yunkang Yang (ORCID: https://orcid.org/0000-0002-8486-3932)
- Peng Jiang (ORCID: https://orcid.org/0000-0002-4218-0092)
- Ruichao He (ORCID: https://orcid.org/0009-0006-9819-7340)
- Yufei Ding (ORCID: https://orcid.org/0000-0002-8716-5793)
- S Wang (ORCID: https://orcid.org/0000-0002-8175-7018)
- Yanjun Guan (ORCID: https://orcid.org/0000-0002-5098-0401)
- Aiyuan Wang
- Wei Liu (ORCID: https://orcid.org/0000-0003-0508-4605)
- Wenjing Xu (ORCID: https://orcid.org/0009-0008-8730-6059)
- Haoye Meng
- Jiajie Chen (ORCID: https://orcid.org/0000-0002-6663-5813)
- Wei Fan (ORCID: https://orcid.org/0000-0002-0586-1892)
- Jianting Ye
- Hongyu Jiang (ORCID: https://orcid.org/0000-0003-0218-845X)
- Cheng Huang
- Yanbin Wu
Institutions
- Capital Medical University (CN)
- Nankai University (CN)
- Chinese PLA General Hospital (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- Beijing Friendship Hospital (CN)
Publication Details
- Journal
- Journal of Orthopaedic Translation
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1016/j.jot.2025.05.005
- Citations
- 4
- Primary Topic
- Tissue Engineering and Regenerative Medicine
- Type
- article
- Field-Weighted Citation Impact
- 8.03