Mitigation of radiation mediated testicular dysfunction by α-tocopheryl succinate: PPAR-γ related pathway
The current study sheds light on the crucial radioprotective role of α-TCS as a PPAR-γ agonist in maintaining testicular function partially through suppressing NF-κB activation and its downstream pro-inflammatory mediators.
Authors
- Maha M. Aziz
- Heba A. Gheita (ORCID: https://orcid.org/0000-0002-5782-2908)
- Noha A. Fadel (ORCID: https://orcid.org/0000-0002-8856-2643)
- Ghada M. Shafey (ORCID: https://orcid.org/0000-0003-2208-560X)
Institutions
- Egyptian Atomic Energy Authority (EG)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1186/s12906-025-04950-7
- Citations
- 2
- Primary Topic
- Selenium in Biological Systems
- Type
- article
- Field-Weighted Citation Impact
- 2.24
Funders
- Cairo University
- Science and Technology Development Fund
- Faculty of Veterinary Medicine, Cairo University