Analysis of the differences in immune indexes of common gene mutations and 5q- chromosome karyotype mutations in MDS

This study investigates the correlation between common MDS mutations and cytokine/lymphocyte subpopulations, preliminarily revealing the interaction between genetic factors and immune markers in myelodysplastic syndrome (MDS), and emphasizes the potential important role of the Th17/Treg axis in the tumor immune microenvironment of MDS, but does not verify the mechanism. The study suggests that fine immune parameters have potential prognostic value in MDS and may guide future MDS treatment strategies.