Body mass index and progesterone receptor in postmenopausal ER-positive/HER2-negative breast cancer: A nation-wide study in Korean breast cancer society and the multi-institutional cohort

In postmenopausal patients with ER+/HER2-breast cancer, the prognostic impact of PgR is modified by BMI. PgR-negativity is a strong predictor of poor outcomes in obese patients but not in non-obese patients.

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Publication Details

Journal
The Breast
Published
2025-06-09
DOI
https://doi.org/10.1016/j.breast.2025.104515
Primary Topic
Cancer Risks and Factors
Type
article
Field-Weighted Citation Impact
0.00

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article

Body mass index and progesterone receptor in postmenopausal ER-positive/HER2-negative breast cancer: A nation-wide study in Korean breast cancer society and the multi-institutional cohort

Byung Kyun Ko, Seung Ho Baek, Sung Gwe Ahn, Joon Jeong et al.
The Breast
Cancer Risks and Factors
article

Body mass index and progesterone receptor in postmenopausal ER-positive/HER2-negative breast cancer: A nation-wide study in Korean breast cancer society and the multi-institutional cohort

Byung Kyun Ko, Seung Ho Baek, Sung Gwe Ahn, Joon Jeong, Young Ah Lim, Doyil Kim, Seok Jin Nam, Soong June Bae, Ho Yong Park, Sanghwa Kim, Soo Youn Bae, Jung Ho Park, Hong Kyu Kim, Janghee Lee, Yeonjoo Kwon, Hee-Joon Kang, Yoowon Kook, Youri Park
article en

Abstract

In postmenopausal patients with ER+/HER2-breast cancer, the prognostic impact of PgR is modified by BMI. PgR-negativity is a strong predictor of poor outcomes in obese patients but not in non-obese patients.

The BreastVol. 82
Ulsan College (KR), Ewha Womans University (KR), Kyungpook National University Hospital (KR), Asan Medical Center (KR), Samsung Medical Center (KR), Seoul National University Hospital (KR), University of Ulsan (KR), Sacred Heart Hospital (NG), Sacred Heart Hospital (US), Ulsan University Hospital (KR), Gangnam Severance Hospital (KR), Hallym University Dongtan Sacred Heart Hospital (KR), Hallym University Sacred Heart Hospital (KR), The Catholic University of Korea Seoul St. Mary's Hospital (KR), Sungkyunkwan University (KR), Catholic University of Korea (KR)
Korean Breast Cancer Society, National Research Foundation, National Research Foundation of Korea
Good health and well-being
Openalex Percentile: Top 80%
Cancer Risks and Factors
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