Exploring the role of glial fibrillary acid protein and neurofilament light chains in patients with hereditary transthyretin amyloidosis with polyneuropathy
These findings support the usefulness of serum NfL as a prognostic tool in ATTRv-PN and highlight the potential involvement of astrocyte activation in disease pathology. Further longitudinal studies are needed to validate these biomarkers for clinical application.
Authors
- Roberta Vassallo
- Luisa Agnello
- Martina Tamburello
- Filippo Brighina (ORCID: https://orcid.org/0000-0001-5875-3126)
- Concetta Scazzone (ORCID: https://orcid.org/0000-0001-7424-8066)
- Anna Masucci
- Anna Maria Ciaccio (ORCID: https://orcid.org/0000-0003-4979-6399)
- Marcello Ciaccio (ORCID: https://orcid.org/0000-0001-6120-9041)
- Vincenzo Di Stefano (ORCID: https://orcid.org/0000-0001-9805-1655)
- Caterina Maria Gambino (ORCID: https://orcid.org/0000-0003-2937-3428)
- Fabio Del Ben (ORCID: https://orcid.org/0000-0002-1880-0669)
Institutions
- Centro di Riferimento Oncologico (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- University of Palermo (IT)
Publication Details
- Journal
- Diagnosis
- Published
- 2025-06-09
- DOI
- https://doi.org/10.1515/dx-2025-0042
- Citations
- 1
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.81